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placental infarction
Posted by scujji on 15:56 9/3/2005:
My first pregnancy resulted in a child who had suffered from severe IUGR (undiagnosed for weeks by an incompetent midwife), and hypoxic brain injury (occurring in utero). Pathology evaluation found multiple infarctions in the shriveled placenta; indeed there had been reversal of blood flow noted on US prior to C-section. Extensive thrombophilia work up on my husband and I, as well as child, revealed only prothrombin II mutation in both husband and son. Nothing in me. I have no significant medical issues, except for being an older mom (was 39 at his delivery, now 44). Our son also carries an unidentified but presumed x-linked disorder (novel mutation), so when we dared to try to become pregnant again, we used donor eggs.
Now that I am pregnant (with twins), I am naturally concerned that the placental problems not recur. The RE agreed w my starting low dose ASA, but the perinatologist we saw with our son's emergency delivery seemed to think that no prophylaxis would be needed with subsequent pregnancies, since the problem “must have” stemmed from the x-linked issue.
Obviously you can’t diagnose the problem, but is there any disadvantage to my taking the ASA, is there a better alternative, and do you have any other suggestions? Thank you!
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