I had an appointment with a HR OB today who said that since my IgG was <6 and my IgM was the only thing elevated at 88 (IgA was also <6), that there is NO association between IgM anticardiolipin antibodies and pregnancy loss and that he would not recommend treatment with lovenox. He said that ONLY IgG anticardiolpin antibodies were associated with pregnancy loss as IgM antibodies do not affect the placental barrier (as IgG antibodies do).
My original labwork from Quest Diagnostics from 12/24/2008 (initial diagnosis) says at the bottom:
"Anti Cardiolipin Abs, IgM: The Antiphospholipid Antibody Symdrome (APS) is a clinical-pathologic correlation that includes a clinical event.....pregnancy loss.... and persistent positive Antiphospholipid Antibodies (IgM or IgG ACA >40 MPL/GPL, IgM or IgG anti-B2GPI antibodies, or a Lupus Anticoagulant....."
I also found this information, specifically question #46 on this link: http://www.apsfa.org/faq/faq5.htm
I will say that neither the rheumatologist nor the regular OB suggested that IgM was less problematic for pregnancies. In fact, the OB I had spoken to previously said he would put me on lovenox if I became pregnant.
Very generally speaking, on various forums, I see that often high IgM numbers are treated with 1xday baby aspirin, if not lovenox.
Needless to say, I'm confused. Can you shed any light on this?
Thanks so much!