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Thread: Help! multiple PGD/IVF attempts failed... implantation

  1. #1
    Join Date
    Jun 2013
    Posts
    7

    Default Help! multiple PGD/IVF attempts failed... implantation

    Hello - would really really appreciate help and ideas

    3 natural pregnancy - 2 stopped due to genetic deformation in the embryo skeleton at week 16, 1 didn't develop

    We know the problematic gene (25% of passing to embryo)

    I'm after 8 rounds of PGD/IVF/Frozen (over 1-2 years):
    - 5 rounds of PGD (long and short cycles)
    - 2 rounds of frozen
    - 1 round of IVF

    In all the rounds I had good response to medicine
    In all rounds I had ~10 eggs, returned 2-3 embryos, day 5 baltocist in almost all attempts, sometimes with hatching

    Histroscope is ok, uterus scanning is ok, blood clotting ok
    I tried pipel before one of the attempts, and steroids in another

    Feel like I tried everything and nothing is working
    I'm lost

    Would love ideas... thoughts... anything I can do? (we are afraid to try natural and get another sick baby)
    Can there be things in implantation we didn't think about? What can we do about them?

    many many many thanks for the help

  2. #2
    Join Date
    Oct 2008
    Posts
    503

    Default

    Very frustrating and sounds like you have done everything right. I guess that your question is best addressed by your RE or by getting a formal 2nd opinion. No magic bullets that I can think of from what you have shared. Sorry.

    Good luck.
    DrG
    Co-Direcor
    Dominion Fertility
    Arlington VA
    www.100infertilityquestions.blogspot.com

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