Immunology may be key to pregnancy loss (updated) by Carolyn Coulam and Nancy Hemenway

Graphis of words associated with immunology

The complexity of the immune system can be key in treating both implantation failure and pregnancy loss.

Immunology May Be Key To Pregnancy Loss

Until the last decade, there was little a couple could do if they suffered from recurrent pregnancy losses. Miscarriages that couldn't be attributed to chromosomal defects, hormonal problems or abnormalities of the uterus were labeled "unexplained," and couples would continue to get pregnant, only to suffer time and again as they lost their babies. New research, however, has provided information on the causes of the heretofore unexplained pregnancy losses allowing more effective treatment enabling women to carry their babies to term.

IVIg THERAPY TEMPLATE LETTER

IVig (intravenous immunoglobulin) is an expensive treatment for both implantation failure as well as multiple miscarriages resulting from reproductive immunological complications. Here is a pre-treatment sample letter for medical necessity or a post treatment appeal for use of this very expensive medication.

PreTreatment with IVIg Letter to Insurance

IVIG is used to treat reproductive immunological problems including multiple miscarriage and implantation failure. This template letter for pre-treatment medical necessity can be sent to insurance companies as a routine appeal for use of IVIg or Intravenous Immunoglobulin

Micromanipulation techniques offer new hope for couples with male factor infertility By Marc Goldstein, M.D., Zev Rosenwaks, M.D., and Linda F. Davey

In any field of medical research, success is often measured in minute degrees, the impact of which may only be known to those whose careers are spent in the laboratories. Occasionally, however, there comes a discovery so astounding that it revolutionizes medical procedure. Such is the case with Intracytoplasmic Sperm Injection, or ICSI, a new infertility treatment utilizing micromanipulation technology that specifically addresses male factor infertility issues. ICSI is so remarkable, in fact, that most treatments previously used have been abandoned in its favor.

Donor Insemination: Sperm Banks Offer Many Choices by Brent Hazelrigg

Couples and individuals facing reproductive choices have many options available to them today. Just a few decades ago, if a patient needed donor sperm their physician made all the choices for them and had little information to share about the donor.

ICSI and SCSA Sperm Diagnostics by Donald P Evenson, Ph.D., HCLD and Kjersten Larson-Cook, Ph.D.

Amy and Todd have been trying to conceive for 2 years. Initially, when they decided to start a family, Todd was certain they would become pregnant very quickly. In his previous marriage, Todd had conceived each of his two children, now 20 and 22 years old, within 3 months. However, on Amy's 35th birthday, the couple realized they could no longer explain away their problem and decided to consult a fertility specialist.

Thatcher's Thoughts on Aspirin, Endometrium and Paternal Aging

To evaluate the effect of aspirin on infertile women with thin endometrium, 114 women were placed into an aspirin group and 122 women into a nonaspirin group

Normal Ranges for a Semen Analysis

A chart with normal ranges for sperm or semen analysis

Platlet Activating Factor and Intrauterine Inseminations by William E. Roudebush, PhD

Platelet-activating factor (PAF) is present in human spermatozoa, and its content has a significant and positive relationship with motility and pregnancy rate.

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