James A. Grifo, M.D., Ph.D. (Video)

Practice Name: 

NYU Fertility Center
660 First Avenue at 38th St. 5th Floor
New York, NY 10016


Reproductive endocrinologist Dr. James Grifo, director of the Fertility Center, discusses the treatment process, research efforts, and patient education at NYU Langone’s Fertility Center.

(212) 263-8990

Since August 1995, Dr. Grifo has been the Director of the Division of Reproductive Endocrinology at the NYU School of Medicine, and also holds the faculty appointment of Professor of Obstetrics and Gynecology at the NYU School of Medicine. He received his MD and Ph.D. degrees at Case Western Reserve Medical School and completed his residency at Cornell University Medical Center. After completing a Fellowship in Reproductive Endocrinology at Yale University, he returned to Cornell and established a medical practice specializing in the treatment of infertility in the Division of Reproductive Endocrinology. He is Board Certified in Obstetrics and Gynecology and Reproductive Endocrinology, as well as being certified by the Accreditation Council for Gynecologic Endoscopy.

Dr. Grifo pioneered techniques called preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS), which examine specific genes and chromosomal number in early embryo development. These procedures determine whether an embryo has genetic abnormalities that can put a pregnancy at risk and increase the odds of miscarriage or of a child being born with health problems.

PGD and PGS require that cells be removed from the embryo, also known as embryo biopsy, considered a safe procedure. I performed the first embryo biopsy that led to a live birth in the United States in 1992.

Dr. Grifo's specific focus is on assisted reproduction, helping people with fertility issues through the use of egg freezing technology and in vitro fertilization (IVF). Specialists in the NYU program were early adopters of egg freezing technology. He pioneered egg-freezing development. The first baby born through the use of egg freezing at NYU Langone was in July 2005. Dr. Grifo contributed heavily to the development of tools used to measure reproductive outcomes, increase the number of successful pregnancies, and reduce the side effects of IVF.

As director of the Fertility Center, Dr. Grifo works with a team of committed physicians to raise the field to a higher standard. Fertility issues are sensitive, and infertility treatment is not an easy process. "When people come to us with the unfulfilled dream of starting a family, we aim to educate them on their options, so they can take an active role in their treatment."  Dr. Griffo and the entire team at NYU dedicate their time ensuring that their fertility treatment experience is as efficient and effective as possible.

Since 1995 at Langone and for many years before, the singular focus and purpose for Dr. Grifo and his colleagues remain to help people achieve their dreams of having children. Through the treatments and research NYU Langone conducts they continue to help build the world, one baby, at a time.  


Conditions and Treatments

fertility, female infertility, male infertility, in vitro fertilization, preimplantation diagnosis, egg freezing, hysteroscopy,minimally invasive surgery, fertility preservation, recurrent miscarriage, 
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  • Professor, Department of Obstetrics and Gynecology
  • Director, Division of Reproductive Endocrinology and Infertility
Education and Training
  • Fellowship, Yale University School of Medicine, Reproductive Endocrinology, 1990
  • Residency, Cornell Medical Center, Obstetrics & Gynecology, 1988
  • MD from Case Western Reserve Univ, 1984
  • PhD from Case Western Reserve Univ, 1982




Reproductive Endocrinology & Infertility
Assited Hatching Services
Blastocyst Services
Clinic operates 365 days a year
Counseling Services
Cryopreservation Services
Donor Egg Program
Donor Sperm Program
Egg Freezing
Embryology Services
Fallopian tube reconstruction
FET Services - Frozen Embryo Transfer
Habitual Aborter - Multiple Miscarriage Services
ICSI Intracytoplasmic Sperm Injection
Infertility Services Only
IVF Program
Mental Health Services - Infertility
Mind Body Program
Psychological Counseling/Screening
Repair or removal of hydrosalpinx
Reproductive Surgery
Singles Treatment of Infertility
Surrogacy services
Testicular biopsy
Tubal anastomosis - Reversal
Varicocele repair
Vasectomy reversal


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