The International Council on Infertility Information Dissemination, Inc

infertility

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    Tuesday, March 19, 2013 - 05:39

    In short, the cause of PCOS is unknown. However, the story is starting to unravel and several important lines of evidence have emerged that offer clues about a central mechanism. The central question remains whether PCOS is a single entity.

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    Tuesday, March 19, 2013 - 05:36

    By treating the insulin resistance, PCOS may be also treated, possibly reversed. While preliminary studies have been very encouraging, there is much to be learned. A major benefit of these medications is that the entire spectrum of problems arising in PCOS appears to be improved.

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    Tuesday, March 19, 2013 - 05:29

    The physical removal of unwanted hair is a useful, if not necessary, adjunctive therapy. Permanent hair removal can be accomplished by electrolysis, which destroys the hair's regeneration mechanism.

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    Tuesday, March 19, 2013 - 05:28

    In the past, ovarian wedge resection, a procedure whereby a portion of the ovary is removed and the ovary sewn back together, resulted a significant reduction in LH and androgen production, reestablishment of regular menses in more than 75 percent of patients and a pregnancy rate of about 60 percent.

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    Tuesday, March 19, 2013 - 05:25

    CC probably is the first-line therapy in PCOS patients who want to become pregnant. In comparison, it is quite safe, inexpensive, easy to use and offers chance of pregnancy in the initial month of use. It works by a pharmacological trick that promotes the release of the pituitary gland's own storage of gonadotropins (FSH and LH).

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    Tuesday, March 19, 2013 - 05:14

    Gonadotropin releasing hormone (GnRH) is a hormone that is released from the hypothalamus and promotes production and release of the gonadotropins (LH and FSH) from the pituitary gland.

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    Tuesday, March 19, 2013 - 05:13

    This group of medications can be used only when not attempting a pregnancy and with some form of adequate birth control. There is at least a theoretical, risk of feminizing the genitals of a male fetus. The value of the agents for PCOS patients is to improve the skin problems that occur with PCOS.

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    Tuesday, March 19, 2013 - 05:11

    Steroids have the ability to suppress adrenal androgen production and may be useful in treatment of PCOS with an adrenal component. Overall, their use is better in theory than practice and they are often discontinued by patients because of unwanted side effects.

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    Tuesday, March 19, 2013 - 05:09

    Oral contraceptives (OC's) are a mainstay of treatment of PCOS in women who do not want to become pregnant. The estrogen component of OC's increases sex steroid binding globulin (SHBG) which bind androgens in the bloodstream and prevent their effects. Increases in SHBG reduce the amount of circulating free testosterone.

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    Tuesday, March 19, 2013 - 05:08

    A progestin is a medication that mimics the action of progesterone. Progesterone is an ovarian hormone produced by the corpus luteum, the structure that forms from the ovarian follicle after ovulation and prepares the uterus for implantation. Unless a pregnancy intervenes, the corpus luteum has a finite lifespan of 10 to14 days. As it fails, progesterone levels fall.

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    Tuesday, March 19, 2013 - 05:04

    While dieting is certainly valuable, it is the most difficult of therapeutic regimens to administer. With weight loss there is often an improvement in endocrine parameters and sometimes a return of menses.

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    Tuesday, March 19, 2013 - 05:03

    There is evidence that PCOS patients had a larger birthweight and were products of pregnancies in which their mother had gestational diabetes. It is clear that the risk of gestational diabetes and probably, pregnancy induced hypertension (PIH, toxemia, preeclampsia) is increased in pregnant women with PCOS.

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