A History of IVF

Overview of the history and statistical outcome of IVF in the United States. In order to understand why insurance is reluctant to cover infertility and in particular IVF (in vitro fertilization), you must first look at the history of IVF and how statistics are gathered and presented.

Viagra and the Endometrial Lining by Geoffrey Sher, M.D.

Pre-ovulatory endometrial thickness and ultrasound appearance, is predictive of potential embryo implantation. While some viable pregnancies may occur with a lining of 8-9mm, very few will occur when the endometrium is less then 8. Find out how viagra could help some people achieve this.

Choosing the Optimal Day for Embryo Transfer by Dlugi, MD

In an effort to reduce the multiple pregnancy rate while maintaining a high overall pregnancy rate, attention was turned to allowing embryos to mature an additional 2 to 3 days in culture achieving a blastocyst stage of development.

How IVF patients may be impacted by embryonic stem cell research. A private choice in a public controversy By K.D. Oakley, PR Manager, NEDC and Jeffrey Keenan, MD, FACOG, HCLD

The fertility industry is on the verge of challenges and changes brought about by the international controversy of embryonic stem cell research. The central issue is the 400,000 excess frozen embryos from in vitro fertilization awaiting a patient’s decision.

Preimplantation Genetic Testing by William Kearns, Ph.D.

Preimplantation genetic diagnosis (PGD) is a state of the art procedure used in conjunction with in vitro fertilization (IVF) to select embryos free of chromosomal abnormalities and specific genetic disorders for transfer to the uterus. These genetic conditions can interfere with embryo implantation, result in pregnancy loss, or in the birth of a child with physical problems, developmental delay or mental retardation.

Understanding and managing Polycystic Ovarian Syndrome (PCOS) by Sam Thatcher, M.D., Ph.D.

Understanding and managing Polycystic Ovarian Syndrome (PCOS) 
by Sam Thatcher, M.D., Ph.D.


It's in the genes

It is a near universal finding that PCOS is genetic, but the heritage is complex. This genetic predisposition is not as simple as brown eyes or blue. The tendency to develop PCOS may be of be inherited from either the mother's side (maternal origin), from the fathers side (paternal origin), or from both sides.

PCOS and insulin resistance

Insulin resistance (IR) is a condition whereby the body steadily becomes less responsive to the actions of insulin. A primary action of insulin is to regulate --lower -- sugar, glucose, levels in the blood.


In short, the cause of PCOS is unknown. However, the story is starting to unravel and several important lines of evidence have emerged that offer clues about a central mechanism. The central question remains whether PCOS is a single entity.

Insulin altering agents

By treating the insulin resistance, PCOS may be also treated, possibly reversed. While preliminary studies have been very encouraging, there is much to be learned. A major benefit of these medications is that the entire spectrum of problems arising in PCOS appears to be improved.


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